Session 1 - Allergens : Production , Purification , Structure Analysis

Crystal structure determination of hyaluronidase, a major bee venom allergen, in complex with an IgG Fab fragment and purification and biophysical characterization of bovine testes hyaluronidase

A study on pollen allergens in China.

OBJECTIVE Allergic disease caused by airborne pollen is a major health problem in China. Intensive study on pollen allergens can be of great help for preventing and treating pollinosis. Four aspects of the study on pollen allergens in China including major allergic pollen in our country, analysis and purification of pollen allergen composition, recombinant pollen allergens and clinical applicat...

Molecular allergology approach to allergic diseases in the paediatric age

Identification, characterization, and purification of allergens are essential for the structural and immunologic studies needed to understand how these molecules induce specific IgE antibody production by the human immune system. Advances in molecular biology techniques have led to the production of recombinant allergens having constant properties, allowing detection of specific IgE directed ag...

مروری بر ارتباط آلرژن های قارچی با آلرژی و بیماری های تنفسی

For years, fungi have been associated with asthma and other reactive airway diseases. In contrast to type I-mediated allergies caused by pollen, fungi cause many allergic diseases such as rhinitis, allergic bronchopulmonary mycoses, hypersensitivity pneumonitis and allergic sinusitis. Aspergillus fumigatus is the most prevalent fungi which causes severe pulmonary allergic diseases, including al...

Isolation and characterization of the 68 kD allergen from house dust mite Dermatophagoides pteronyssinus

House dust mites (HDM) represent a major source of allergens, contributing to the increasing incidence of type I hypersensitivity disease worldwide. Over 30 different IgE-binding proteins from the HDM extract were detected. Although group 1 and 2 have been identified as major allergens, due to the safety and efficacy of allergy diagnosis and immunotherapy, there is a need to carefully evaluate ...